Rabbit VX2 Liver Tumor Model: A Review of Clinical, Biology, Histology, and Tumor Microenvironment Characteristics. Pascale F, Pelage JP, Wassef M, Ghegediban SH, Saint-Maurice JP, De Baere T, Denys A, Duran R, Deschamps F, Pellerin O, Maeda N, Laurent A, Namur J. Front Oncol (2022)

Vandetanib-eluting Radiopaque Beads: Pharmacokinetics, Safety, and Efficacy in a  Rabbit Model of Liver Cancer. Duran, R. et al. Radiology 293, 695–703 (2019).

Midterm Recanalization after Arterial Embolization Using Hydrogel-Coated Coils versus Fibered Coils in an Animal Model. Fohlen, A. et al. J Vasc Interv Radiol 30, 940–948 (2019).

Evaluation of novel formulations for transarterial chemoembolization: combining elements of Lipiodol emulsions with Drug-eluting Beads. Caine, M. et al. Theranostics 9, 5626–5641 (2019).

Lymphatic Transport and Lymph Node Location of Microspheres Subcutaneously Injected in the Vicinity of Tumors in a Rabbit Model of Breast Cancer. Pascale, F. et al. Pharm Res 35, 191 (2018).

Peripheral Embolization Using Hydrogel-Coated Coils Versus Fibered Coils: Short-Term Results in an Animal Model. Fohlen, A. et al. Cardiovasc Intervent Radiol 41, 305–312 (2018).

Comparison of microsphere penetration with LC Bead LUMI versus other commercial microspheres. Caine, M. et al. J Mech Behav Biomed Mater 78, 46–55 (2018).

Hepatic Intra-arterial Delivery of a ‘Trojan-horses’ Gene Therapy: A Pilot Study  on Rabbit VX2 Hepatic Tumor Model. Pellerin, O. et al. Cardiovasc Intervent Radiol 41, 153–162 (2018).

Potentiation of doxorubicin efficacy in hepatocellular carcinoma by the DNA repair inhibitor DT01 in preclinical models. Herath, N. I. et al. Eur Radiol 27, 4435–4444 (2017).

Laparoscopic subperitoneal injection of chemo-loaded particles lowers tumor growth on a rabbit model of peritoneal carcinomatosis. Pascale, F. et al. Tumour Biol 39, 1010428317698381 (2017).

Antitumoral Effect of Sunitinib-eluting Beads in the Rabbit VX2 Tumor Model. Bize, P. et al. Radiology 280, 425–435 (2016).

bFGF Up-regulation Reduces Spontaneous Necrosis of VX2 Tumors Without Increasing  Tumoral Microvascular Density. Pascale, F. et al. Anticancer Res 36, 3315–3320 (2016).

Comparative Chemosensitivity of VX2 and HCC Cell Lines to Drugs Used in TACE. Pascale, F. et al. Anticancer Res 35, 6497–6503 (2015)

Safety and efficacy compared between irinotecan-loaded microspheres HepaSphere and DC bead in a model of VX2 liver metastases in the rabbit. Namur, J. et al. J Vasc Interv Radiol 26, 1067-1075.e3 (2015).

Automated Quantification of Tumor Viability in a Rabbit Liver Tumor Model after Chemoembolization Using Infrared Imaging. D’inca, H. et al. Am J Pathol 185, 1877–1888 (2015).

Toxicity of doxorubicin on pig liver after chemoembolization with doxorubicin-loaded microspheres: a pilot DNA-microarrays and histology study. Verret, V. et al. Cardiovasc Intervent Radiol 36, 204–212 (2013).

Irinotecan loaded in eluting beads: preclinical assessment in a rabbit VX2 liver  tumor model. Rao, P. P. et al. Cardiovasc Intervent Radiol 35, 1448–1459 (2012).

Locoregional drug delivery using image-guided intra-arterial drug eluting bead therapy. Lewis, A. L. et al. J Control Release 161, 338–350 (2012).

Modified model of VX2 tumor overexpressing vascular endothelial growth factor. Pascale, F. et al. J Vasc Interv Radiol 23, 809-817.e2 (2012).

Embolization of hepatocellular carcinoma with drug-eluting beads: doxorubicin tissue concentration and distribution in patient liver explants. Namur, J. et al. J Hepatol 55, 1332–1338 (2011).

In vitro evaluation of (S)-ibuprofen toxicity on joint cells and explants of cartilage and synovial membrane. Bedouet, L. et al.. Toxicol In Vitro 25, 1944–1952 (2011).

Pulmonary artery chemoembolization in a sheep model: Evaluation of performance and safety of irinotecan eluting beads (DEB-IRI). Baylatry, M.-T. et al. J Biomed Mater Res B Appl Biomater 98, 351–359 (2011).

IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen. Verret, V. et al. Eur J Pharm Sci 42, 489–495 (2011).

The arterial distribution of Embozene and Embosphere microspheres in sheep kidney and uterus embolization models. Verret, V. et al. J Vasc Interv Radiol 22, 220–228 (2011).

Influence of degradation on inflammatory profile of polyphosphazene coated PMMA and trisacryl gelatin microspheres in a sheep uterine artery embolization model. Verret, V. et al. Biomaterials 32, 339–351 (2011).

Arterial distribution of calibrated tris-acryl gelatin and polyvinyl alcohol embolization microspheres in sheep uterus. Laurent, A. et al. Cardiovasc Intervent Radiol 33, 995–1000 (2010).

Drug-eluting beads for liver embolization: concentration of doxorubicin in tissue and in beads in a pig model. Namur, J. et al. J Vasc Interv Radiol 21, 259–267 (2010).

Infrared microspectroscopy analysis of ibuprofen release from drug eluting beads  in uterine tissue. Namur, J. et al. J Control Release 135, 198–202 (2009).

Anti-inflammatory effect of ibuprofen-loaded embolization beads in sheep uterus. Wassef, M. et al. J Biomed Mater Res B Appl Biomater 86, 63–73 (2008).

MR imaging detection of superparamagnetic iron oxide loaded tris-acryl embolization microspheres. Namur, J. et al. J Vasc Interv Radiol 18, 1287–1295 (2007).

Arterial distribution of calibrated tris-acryl gelatin and polyvinyl alcohol microspheres in a sheep kidney model. Laurent, A. et al. Invest Radiol 41, 8–14 (2006).