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EMBOLIZATION PARTICLES

Understanding the action of resorbable in pre clinical models

Namur J (Invited Speaker)

MSK Global Embolization Symposium and Technologies (GEST) PARIS, 20-21 Jan 2023

 

Evaluation of embolization devices & drug-eluting embolics in Swine

Namur J (Invited Speaker)

Minipig Research Forum (MRF), Barcelona, 16-18 May, 2018

 

In vivo experiment Lipiodol drug-eluting beads resorbable material: how to quantify the embolic effect drug elution

Namur J (Invited Speaker)

Cardiovascular and Interventional Radiology Society of Europe (CIRSE), Lisbon 22-25 Sept, 2018

 

Vandetanib-eluting radiopaque beads: Pharmacokinetics and proof of concept in rabbit VX2 liver tumour model

Duran R, Namur J, Pascale F, Czuczman P, Bascal Z, Kilpatrick H, Whomsley R, Ryan S, Lewis AL, Denys A.

Cardiovascular and Interventional Radiology Society of Europe (CIRSE),  Lisbon 22-25 Sept, 2018

 

DEBS: The Right Dose and Ideal Release Mechanism Are Yet to Be Determined

Namur J (Invited Speaker)

Global Embolization Symposium and Technologies (GEST) NEW-YORK, 5-8 May 2016

 

In Vivo Behavior of Drug-Eluting Embolics

Namur J (Invited Speaker)

Global Embolization Symposium and Technologies (GEST) NEW-YORK, 5-8 May 2016

 

Comparison of the different drug-eluting bead platforms

Namur J (Invited Speaker)

European Conference on Interventional Oncology (ECIO) DUBLIN 17-20 April 2016

 

In vivo behaviour of drug-eluting embolics (DEE): past concepts & present evidence

Namur J (Invited Speaker)

Global Embolization Symposium and Technologies (GEST) SEVILLA, Spain, 24-27 June 2015

 

DEBS: Do Drug Dose and Release Characteristics Translate to Differing Outcomes?

Namur J (Invited Speaker)

Global Embolization Symposium and Technologies (GEST) SAN FRANSISCO 1-4 Mai 2014

 

Safety and efficacy compared for two doxorubicin loaded microspheres in liver VX2 model

Namur J, Pascale F, Dinca H, Ghegediban SH, Saint Maurice JP, Verret V, Maeda N, Manfait M, Wassef M, Laurent A.

Society of Interventional Radiology - SIR SAN DIEGO March 22-27, 2014

 

Doxorubicin eluting microsphere: is there a size effect ? Comparison of two sizes in VX2 tumor model

Namur J, Pascale F, Dinca H, Ghegediban SH, Saint Maurice JP, Maeda N, Verret V, Manfait M, Wassef M, Laurent A

Society of Interventional Radiology - SIR SAN DIEGO March 22-27, 2014

 

Excellent response of VX2 liver metastases to iri delivered from 2 types of microspheres

Namur J, Pascale F, Sterba M, Maeda , Ghegediban S, Verret V, Wassef M, Laurent A

Society of Interventional Radiology - SIR SAN DIEGO March 22-27, 2014

 

Necrosis and repair in normal liver after doxorubicin chemoembolization

Verret V, Molliex A, Namur J , Ghegediban SH , Laurent A, Wassef M;

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Lisbon 15-19 sept 2012

 

Why do small size doxorubicin-eluting microspheres induce more tissue necrosis than larger ones? A comparative study in healthy pig liver

D’inca H, Pelage JP, Baylatry MT, Ghegediban SH, Pascale F, Manfait M, Wassef M, Laurent A, Namur J

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Lisbon 15-19 sept 2012

 

In vivo distribution of different sizes of bland and drug-loaded microspheres in a pig liver model

Ghegediban SH, Namur J, Pelage JP, Pascale F, Laurent A, Wassef M

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Lisbon 15-19 sept 2012

 

Hydrogel-coated coils versus fibered coils in an animal model of peripheral embolization: mechanism of occlusion in a short-term study

Fohlen A, Ghegediban SH, Namur J, Laurent A, Wassef M, Pelage JP

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Lisbon 15-19 sept 2012

 

Mid-Term Follow-Up after Embolization Using Hydrocoils vs Fibered coils in an Animal Model: Angiographic and Pathologic evaluation - Communication orale

Pelage JP, Fohlen A, Ghegediban SH, Namur J, Laurent A, Wassef M

Society of Interventional Radiology - SIR SAN FRANCISCO March 24-29, 2012

 

Mid-term recanalization after embolization using hydrogel-coated coils versus fibered coils in an animal model

Pelage JP, Ghegediban SH, Fohlen A, Namur J, Laurent A, Wassef M

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Lisbon 15-19 sept 2012

 

The choice of small size microspheres for a homogeneous distribution in embolized tissue

Ghegediban SH, Wassef M, Pelage JP, Pascale F, Verret V, Namur J, Laurent A

Society of Interventional Radiology - SIR SAN FRANCISCO March 24-29, 2012

 

The size of drug loaded microspheres influences the local drug delivery and toxicity

Namur J, Ghegediban SH, Pelage JP, Verret V, Manfait M, Wassef M, Laurent A;

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Munich 10-14 sept 2011

 

Bronchial artery embolization with rapamycin-eluting beads: blood and lung concentrations in a sheep model

Pelage JP, Baylatry MT, Ghegediban SH, Wassef M, Lewis AL, Laurent A

Society of Interventional Radiology - SIR Chicago FL March 25-30, 2011

 

Plasmatic and lung concentrations after irinotecan-elutingbeads (DEBIRI) embolization of pulmonary artery alone vs. combined with bronchial artery embolization in a sheep model

Baylatry MT, Pelage JP, Lacombe P, Wassef M, Ghegediban SH, Lewis AL, Fernandez C, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Valencia 2-6 Oct 2010

 

Pulmonary artery embolization with and without additional bronchial artery embolization using Irinotecan eluting beads: tolerance in a sheep model

SH Ghegediban, Pelage JP, Wassef M, Baylatry MT, Lewis AL, Lacombe P, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Valencia 2-6 Oct 2010

 

Degradation and inflammation of embolization microspheres: Embozene vs Embosphere in a UAE sheep model

Verret V, Wassef M, Pelage JP, Ghegediban SH, Schwartz-Cornil I, Golzarian J, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Valencia 2-6 Oct 2010

 

Deformation influences arterial distribution: Embozene vs Embosphere in sheep kidney and uterus

Verret V, Pelage JP, Wassef M, Ghegediban SH, Golzarian J, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Valencia 2-6 Oct 2010

 

FTIR-imaging as a quantification method of drug delivery in vivo

Namur J, D’Inca H, Lewis AL, Laurent A, Manfait M

SPEC2010 Manchester, June 26th and July 1st 2010.

ANIMAL MODELS AND EVALUATION (Biology, biochemistry, imaging, genomics)

Nature of the angiogenesis in the repair process after doxorubicin chemoembolization in the normal liver of pigs

Verret V,  Molliex A, Namur J, Ghegediban SH, Wassef M, Pascale F, Pelage JP, Laurent A

Society of Interventional Radiology - SIR SAN FRANCISCO March 24-29, 2012

 

Molecular biology profile of VX2 carcinoma in the rabbit liver

Verret V, Pascale F, Marturano A, Ghegediban S, Wassef M, Namur J, Laurent A

Society of Interventional Radiology - SIR SAN FRANCISCO March 24-29, 2012

 

Mechanisms of doxorubicin toxicity on liver after TACE with doxorubicin-loaded microspheres in pigs

Verret V, Wassef M, Ghegediban SH, Pelage JP, Namur J, Bonneau M, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Munich 10-14 sept 2011

 

Angiogenesis and cell death after liver embolization with bland vs doxorubicin-loaded microspheres : a gene expression study in a pig model

Verret V, Pelage JP, Namur J, Ghegediban SH, Wassef M, Jouneau L, Bonneau M, Laurent A

Society of Interventional Radiology - SIR Chicago FL March 25-30, 2011

 

DNA-microarray to profile the inflammation on embolization microspheres: comparison of two materials at 1 and 4 week in a sheep UAE model

Verret V, Schwartz-Cornil I, Pelage JP, Jouneau L, Ghegediban S, Wassef M, Golzarian J, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Valencia 2-6 Oct 2010

"Magna Cum Laude"

 

Tissular diffusion of ibuprofen from embolization beads

Verret V,  Bevilacqua C, Schwartz-Cornil I, Pelage JP, Wassef M, Namur J, Bedouet L, Lewis AL, Martin P, Laurent A

Society of Interventional Radiology - SIR Chicago FL March 25-30, 2011

 

Fast and automated assessment of tumor response: Infrared imaging

D’inca H, Ghegediban SH, Wassef M, C. Gobinet, Namur J, Pascale F, Laurent A, Manfait M

American Association for Cancer Research AACR SAN DIEGO 5 -9 Avril 2014

 

Are VX2 tumor cells sensitive to antineoplastic drugs used in chemoembolization? A comparative study  of 12 drugs on VX2 vs HepG2 cells

Pascale F, Bedouet L, Namur J, Baylatry MT, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Barcelone, 14-18 sept 2013

 

Infrared Imaging as a Novel Method to Evalaute the Efficacy of a Locoregional Treatment in a Liver Tumor Model

D’inca H, Ghegediban SH, Wassef M, Gobinet C, Namur J, Pascale F, Laurent A, Manfait M

European Conference on the Spectroscopy of Biological Molecules ECSBM, Oxford UK, 25-30 August 2013

1er Prix Poster 

 

Liver VX2 tumors from VEGF transfected cells have a higher intratumoral vascular density and a lower necrosis than classical VX2 liver tumors 

Pascale F, Ghegediban SH, Bonneau M, Bedouet L, Verret V, Namur J, Schwartz-Cornil I, Wassef M, Laurent A

CIRSE (Cardiovascular and Interventional Radiology Society of Europe), Munich 10-14 sept 2011

 

Improvement of VX2 tumor model by transfection with vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF)

Pascale F, Wassef M, Ghegediban SH, Bonneau M, Bedouet L, Verret V, Schwartz-Cornil I, Namur J, Laurent A

Society of Interventional Radiology - SIR Chicago FL March 25-30, 2011

 

Cutaneous wound repair studied by FTIR microspectroscopy

Namur J, Wassef M, Floch P, D’Inca H, Laurent A, Manfait M

SPEC2010 Manchester, June 26th and July 1st 2010.

PCRO